The authors describe a method-validation-by-design (MVbD) approach to validate a method over a range of formulations using both design-of-experiment and quality-by-design principles to define a design ...

Artificial intelligence and machine learning can help overcome poor solubility and bioavailability. Artificial intelligence (AI) and machine learning (ML) in the biopharmaceutical industry have been ...

High level of microorganisms should not be present in non-sterile products for human use as they may cause adverse incidents. As an expert specializing in drug formulation, CD Formulation announces to ...

Lipid nanoparticle formulation has increased over the past two decades. LNPs have proven to be effective nano-based delivery vehicles for cytotoxic chemotherapeutic drugs, nucleic acid therapies and ...

Nonclinical dose formulation analysis methods are used to confirm test article concentration and homogeneity in formulations and determine formulation stability in support of regulated nonclinical ...

(Boca Raton, Florida) Stellar Materials LLC has introduced a new line of refractory products called the Thermbond 7200 Series that can substantially reduce the cost of most furnace repairs through its ...

CAMBRIDGE, MA -- About 60 percent of drugs on the market have hydrophobic molecules as their active ingredients. These drugs, which are not soluble in water, can be difficult to formulate into tablets ...

Mathematics of Computation, Vol. 79, No. 272 (OCTOBER 2010), pp. 2001-2032 (32 pages) We derive in this paper a unified framework for a priori and a posteriori error ...