Early detection of safety liabilities of new therapies is a critical biopharmaceutical challenge. Addressing this challenge could significantly advance drug discovery. Advanced human cell models, ...

Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...

Peripheral neuropathy (PN) is a dose-limiting side effect of chemotherapeutic and antibody drug conjugate (ADC) treatment which significantly impacts patients’ quality of life. Despite a high clinical ...

In this whitepaper, Sartorius discusses the need to replace animal testing with advanced in vitro human cell models for pharmaceutical, chemical, and cosmetic development as, with only 5-10% of ...

Researchers have developed a vascularized organoid model of hormone secreting cells in the pancreas. The advance promises to improve diabetes research and cell-based therapies. Researchers led by ...

Today, the Chan Zuckerberg Initiative (CZI) and NVIDIA announced an expanded collaboration to accelerate life science research by driving development and adoption of virtual cell models through tools, ...

New confocal fluorescence imaging minimizes photobleaching and phototoxicity effects, capturing clear images of live 3D culture Industry-leading throughput enables real-time analysis of up to six ...

Yusuf Roohani, PhD, machine learning group lead at the Arc Institute, is among a team of researchers training artificial intelligence (AI) models with transcriptome data to predict how cell gene ...

The human cell is a miserable thing to study. Tens of trillions of them exist in the body, forming an enormous and intricate network that governs every disease and metabolic process. Each cell in that ...